LONG ESSAY QUESTIONS
  1. Classify Chlamydia. Describe the pathogenesis and laboratory diagnosis of Chlamydial infections.
  2. Classify Enterobacteriaceae and describe the laboratory diagnosis of urinary tract infection.
  3. Classify Herpes group of viruses. Describe pathogenesis and clinical features of herpes simplex infection.
  4. Classify Mycobacteria and give brief account of atypical Mycobacteria.
  5. Classify Mycobacteria and name the diseases produced by them. Describe the laboratory diagnosis of pulmonary tuberculosis.
  6. Classify Staphylococci. Describe the pathogenicity and laboratory diagnosis briefly.
  7. Classify anaerobic spore bearers. Describe the laboratory diagnosis of tetanus.
  8. Classify antigen-antibody reactions and describe their applications in laboratory diagnosis of infectious diseases.
  9. Classify atypical Mycobacteria and describe the characteristics of various atypical Mycobacteria.
  10. Classify food poisoning with examples. Describe the laboratory diagnosis of food poisoning.
  11. Classify immunity. Describe artificially acquired passive immunity.
  12. Classify microfilaria and describe a method of finding live microfilaria in blood.
  13. Classify spirochetes and discuss the laboratory diagnosis of syphilis.
  14. Classify spirochetes. Describe briefly non specific serological tests used for the diagnosis of syphilis
  15. Classify spirochetes. Describe the laboratory diagnosis of leptospirosis.
  16. Classify streptococci. Add a note on serological diagnosis of streptococcal infections.
  17. Classify streptococci. List the lesions caused by Streptococus pyogenes. Add a note on ASO test.
  18. Classify the family Enterobacteriaceae. Describe in detail the laboratory diagnosis of enteric fever.
  19. Classify the methods of sterilization and disinfection. Describe sterilization methods by autoclave.
  20. Classify trematodes. Write briefly about the life cycle and pathogenesis of Schistosoma hematobium.
  21. Compare and contrast the cell mediated immunity and humoral immunity with respect to their activity.
  22. Define and classify Hypersensitivity. Briefly write about type I hypersensitivity reactions.
  23. Define and classify hypersensitivity. Enumerate the differences between immediate and delayed hypersensitivity.
  24. Define and classify immunity. Write briefly on innate immunity.
  25. Define complement and describe the alternate pathway of complement activation. Give one example.
  26. Define the morphology and pathogenesis of rabies virus. Add a note on prophylaxis of rabies.
  27. Describe briefly the mechanism and application of agglutination tests.
  28. Describe morphological, cultural and toxic characters of Corynebacterium diphtheriae.
  29. Describe the biological functions of complement.
  30. Describe the different methods of cultivation of viruses.
  31. Describe the laboratory diagnosis of pulmonary tuberculosis. Mention the tests done for identification of M.tuberculosis.
  32. Describe the laboratory methods employed in the diagnosis of viral infections.
  33. Describe the mechanism of genetic exchange in bacteria.
  34. Describe the mechanism of precipitation reaction. List several ways in which the precipitation tests can be useful.
  35. Describe the morphology and cultural characteristics of Vibrio cholera. Mention the laboratory diagnosis and prophylaxis of cholera.
  36. Describe the morphology and life cycle of Leishmania donovani. Write briefly on the laboratory diagnosis of kala-azar.
  37. Describe the morphology, cultural characters and pathogenicity of Bacillus anthracis. Outline the procedure in laboratory diagnosis of an infection by this organism.
  38. Describe the morphology, life cycle and pathogenesis of Wuchereria bancrofti.
  39. Describe the morphology, life cycle and pathogenicity of Echinococcus granulosus.
  40. Describe the principle and uses of fluorescence microscopy.
  41. Describe the stool in intestinal amoebiasis giving both macroscopic and microscopic findings.
  42. Describe the structure of typical bacterial cell. List the function of each part.
  43. Describe the structure, classes and functions of immunoglobulin.
  44. Describe the use of embryonated egg in virology.
  45. Describe the various causes of dysentery in tropics. Describe in detail the laboratory diagnosis of bacillary dysentery.
  46. Differentiate between the terms infection and infectious diseases. Describe in detail microbial factors responsible for pathogenicity.
  47. Discuss in detail the laboratory diagnosis of diphtheria. What are the prophylactic measures adopted against this disease?
  48. Discuss the laboratory diagnosis of bacterial diarrhoea.
  49. Discuss the laboratory diagnosis of enteric fever and its prophylaxis.
  50. Discuss viral hepatitis with particular reference to laboratory diagnosis and prophylaxis.
  51. Enumerate all antigen-antibody reactions and describe in detail any one of them.
  52. Enumerate all the respiratory viruses. Outline the steps taken to establish the viral etiology in the laboratory.
  53. Enumerate different members of sporozoa. Describe the laboratory diagnosis of malaria. Add a note on prophylaxis of malaria.
  54. Enumerate the bacteria causing diarrhoea and write in detail the laboratory diagnosis of any one bacterial infectious diarrhoea.
  55. Enumerate the different classes of immunoglobulins. Draw a neat diagram of the immunoglobulin molecule and label the parts. Write the characteristics of the different immunoglobulins.
  56. Enumerate the growth requirement of bacteria. Describe in detail the methods of anaerobic culture.
  57. Enumerate the helminths that cause anemia. Briefly describe the life cycle of Ancylostoma duodenale.
  58. Enumerate the intestinal nematodes parasitic to man. Describe the life cycle and pathogenicity of Necator americanus
  59. Enumerate the organism causing urinary tract infections. Outline the steps in the laboratory diagnosis of urinary tract infection.
  60. Enumerate the parasites causing anemia. Describe the life cycle and laboratory diagnosis of any one of these.
  61. Enumerate the somatic (tissue) nematodes. Describe in brief the life cycle and pathogenesis of Dracunculus medinensis.
  62. Enumerate various pathogenic Clostridia. Describe the morphology and laboratory diagnosis of Clostridium tetani.
  63. List STD. Describe the laboratory diagnosis of acute and chronic gonorrhoea in both the sexes.
  64. List the Corynebacteria found in human beings. Describe the laboratory diagnosis and prophylaxis of diphtheria.
  65. List the aroboviruses prevalent in India. Add a note on KFD.
  66. List the bacterial agents encountered in pyogenic meningitis. Discuss the steps in laboratory diagnosis of meningitis caused by any one of them.
  67. Mention the viruses causing Hepatitis. Describe the laboratory diagnosis of serum hepatitis and its prophylaxis.
  68. Name the Herpes viruses. Discuss their role in human oncogenesis.
  69. Name the agents of Pyrexia of Unknown Origin. Describe the pathogenesis, laboratory diagnosis and prophylaxis of typhoid fever.
  70. Name the causes of bacterial meningitis. Describe the laboratory diagnosis of cerebrospinal fever.
  71. Name the infections acquired from rats. Describe the pathogenicity and laboratory diagnosis of leptospirosis.
  72. Name the malaraial parasites of man. Describe the sexual cycle of the parasite in detail.
  73. Name the malarial parasite. Describe the life cycle and laboratory diagnosis of malaria.
  74. Name the malarial parasites. Write briefly on life cycle, pathogenicity and laboratory diagnosis of Plasmodium falciparum.
  75. Name the parasites that can be detected in blood smear. Describe the morphology of gametocytes of Plasmodium falciparum.
  76. What are heterotrophic bacteria? Discuss the nutritional and physical requirements for the growth of bacteria.
  77. What are immunoglobulins? Outline the role they play in host defence. Add a note on clonal selection theory.
  78. What is agglutination? Discuss the mechanism involved and practical uses of various types of agglutination reactions.
  79. What is drug resistance? Describe the mechanism of development of drug resistance in bacteria.
  80. What is meant by antibiotic susceptibility testing? List the various methods used and write in brief the mode of action of antibiotics.
  81. Write a short essay on the laboratory diagnosis of dermatophytosis.

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